Women's Health

Ginette-35

Zhinet - 35 (tsyproteronu) used oral contraceptives for women to be anti-androgen therapy. Tsyproteronu acetic acid can be combined with the use of estrogen to control etinil idiopathic hirsutism.

Ginette-35 0.035+2 mg

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Product description

Safety information

Side Effects

Drug Name

Zhinet - 35 (tsyproteronu)

Drug Uses

Tsyproteronu acetic acid can be combined with the use of estrogen to control etinil idiopathic hirsutism.
Each bladder 28 of the active hormone pills containing 21 pills, coated tablets, 0035 mg and 2 mg of each estrogen ethinyl estradiol acetate plus 7 tsyproteronu active non-hormonal contraceptives.
For the treatment of severe acne, acne, particularly androgen-dependent, associated with inflammation, seborrhea, or distorted. Zhinet - 35 oral contraceptives for women to be anti-androgen therapy.

How to use

Coagulation system diseases and family history of thromboembolic disease, especially in the young, should be excluded.
If diarrhea or vomiting, and other non-hormonal contraception should be used to prevent pregnancy. Pills take the next step in your usual time to prevent bleeding canceled.
Tablets should be taken about the same time less than 24 hours a day, the biggest benefit. Additional non-hormonal contraception should take preventive measures. Do not double dose. This approach should be followed as long as contraception is needed.
Additional contraceptive measures must be taken to the first 14 days of the first round and missed contraceptive care.
First cycle: the patient must take the first pill on the first day of the cycle (cycle of the first day, first day of menstrual bleeding).
Patients should consult a doctor, if it is a long-term, persistent bleeding. , People should be one tablet a day later, a sequence of arrows at the same time, until all tablets were taken. Tablets can be taken with meals to reduce nausea.
Missed dose: as soon as possible in the next 12 hours, last but not almost time for your next dose. Pregnancy must be excluded. Prior to this Zhinet - 35, the appropriate medical care (including gynecological) examination and the history of the patient will be carefully assessed.
The next round: the new package must run on the next day after a packet, beginning with the corresponding day of silver bars. The first piece should be from the silver box (calendar pack), because the relevant date specified in the panel.
Androhin producing adrenal tumors or defective enzyme must be excluded from the purpose of Zhinet - 35 treatment hirsutyzmu. Periodic medical examination is recommended during use.
Treatment of acne androgen dependent: dosage, as a contraceptive.
Spots may occur, but usually stops spontaneously.

Drug Class and Mechanism

Androgen receptor antagonist Tsyproteronu acetate. Combination of sebaceous gland activity is inhibited tsyproteronu.
Ethinyl estradiol is a synthetic estrogen combined with inhibition of ovulation tsyproteronu mid-cycle peak by inhibiting progesterone and pituitary release of follicle stimulating hormone.
Tsyproteronu increased viscosity of mucus that causes cervical cancer acetate, so that it is hostile to sperm penetration.
This combination also affects the endometrium, which may cause adverse endometrial implantation of fertilized eggs. He prohestohennoyi activity and inhibition of gonadotropin secretion.

Missed Dose

Pills take the next step in your usual time to prevent bleeding canceled. If you miss a dose Zhinet - 35, as soon as possible in the next 12 hours Last but not almost time for your next dose. Additional non-hormonal contraception should take preventive measures. Do not double dose.

Storage

Maintaining Zhinet - 35 away from children and pets from the arrival. Shop Zhinet - 35 below 86 degrees Fahrenheit (30 degrees C). Keep away from heat, humidity and light. Do not store in the bathroom.

Warnings/Precautions

It should not be to the patient history of thromboembolic disease. This may include myocardial infarction, pulmonary embolism, venous thrombosis and stroke.
Contraindicated in patients with severe chronic depression and sickle cell anemia. He said that the use Zhinet - 35 will be stopped, if any of the following symptoms:

1. Migraine or severe headache beginning of a new patient.
Breast-feeding.
Women smoking more than 15 a day, at least 20% of high risk of serious cardiovascular side effects.
When not in use, in children and men.
7. Pregnancy.
This combination should not be a permanent appointment after the recent evacuation of the bladder into the urine and plasma luteinizing hormone levels back to normal. Smoking increases the risk of myocardial infarction.

Liver disease and cancer, or spend money. Recommended to stop oral contraceptives 4 to 6 weeks before the surgery.

6.
Known or suspected breast cancer.
The composition of any allergies. If the blood pressure significantly product should stop using it.
Oral contraceptives are contraindicated in patients with estrogen-dependent tumors, functional ovarian cysts, Durbin, Johnson or Rotor syndrome, in violation of lipid metabolism, especially the liver, brain ischemia, ischemic heart disease, thrombophlebitis, deterioration otosclerosis, the history of itching in the last pregnancy, undiagnosed vaginal bleeding, herpes, recurrent cholestatic jaundice or porphyria.
The typical migraine patients should not use combined oral contraceptives.

3. In the first sign of thromboembolic diseases such as lung, brain, vascular insufficiency, thrombophlebitis, cerebral hemorrhage, retinal thrombosis, coronary and mesenteric thrombosis.

Taboo:
Oral contraceptives should not be used in known or suspected pregnancy, because it may cause serious damage to the fetus.

5. If the product should stop persistent upper abdominal pain and development of hepatitis or jaundice.
Relative contraindications (These patients need medical guidance):
Diabetes, seizures, hypertension, epilepsy, chorea, multiple sclerosis, renal insufficiency, asthma, depression, varicose veins, heart failure, gallbladder disease, patients wearing contact lenses, who obese patients, edema or other conditions affecting . Risk benefit should be considered in patients with endometriosis and uterine fibroids.

2. When there is a gradual or sudden loss of vision or hearing. This risk increases with age, is quite obvious women over 35 years. Women using oral contraceptives should be strongly recommended not to smoke.

4. Surgery or prolonged bed rest, because this may increase the risk of thrombotic events.

Possible Side Effects

Amenorrhea after long-term use of oral contraceptives may occur.
Increased risk of cervical cancer, although the report may involve other factors. Nausea, vomiting, headache, chloasma, skin pigmentation, vaginal candidiasis, gastrointestinal upset, Tizhongzengjia and surrounding edema. Thrombosis may be more common in women Blood A, B or AB.
Hypertension may occur.
Changes in hair pattern, skin reactions and anemia were reported. Increase in the incidence of women who are obese or have high blood pressure, if they. In the case of severe upper abdomen, liver enlargement, or abdominal bleeding, liver tumors should be excluded. The following side effects may occur:
Changes include breast tenderness, expansion and secretion.
Liver function can be slowed.
The incidence of cardiovascular disease than women who have diabetes, high cholesterol and family hyperlipoproteinaemia. There may be changes, carbohydrate and fat metabolism. Where irregular menstruation or amenorrhea occurred in the past, caution recommended.
Changes in menstruation (spotting, breakthrough bleeding, amenorrhea) temporary mizhmenstrualnyh bleeding, change in libido, depression, abdominal pain or bloating cramps, dizziness may occur. Seems to increase the number of benign liver.
Gall bladder obstruction, or hepatitis may occur. Contact lens intolerance, reports, and vision can deteriorate in the short-sighted patients.
Combined oral contraceptives in women with cardiovascular disease and mortality rates significantly higher than the control increased slightly. Stroke, heart attack and venous thrombosis more common in women over 35 years, especially if they use contraceptives, or smoking more than 5 years.
Hepatoblastoma have been reported. Regular blood pressure control, including verification of pre-treatment recommendations. The incidence rate of about 1% of the users.

More Information

In any case, did not receive oral contraceptives should stop the other contraceptive methods. SPECIAL NOTE:
Hormonal contraceptives prior to administration, patients must undergo a medical examination of her medical history to end, must be carefully analyzed. Breakthrough bleeding can occur with high doses of vitamin C withdrawal
Some of the effectiveness of anticoagulants, hypoglycemic and anti-depressant drugs may reduce the blood concentration of cyclosporine, can increase simultaneously.
Hormonal contraception may not be recommended for more time to antibiotic treatment, and after seven days. Regular medical examinations should be done in the use of oral contraceptives. These long-term antibiotic therapy need only take extra precautions during the first two weeks of antibiotic treatment.
It was reported that pregnant women take anti-epileptic (barbiturates, prymidon, phenitoin, carbamazepine). Breakthrough bleeding or spotting possible signs of reduced contraceptive effect. Some laboratory tests may be altered, including hormone testing, blood coagulation, thyroid function, glucose, liver function tests and serum triglycerides. Antihypertensive efficacy, β-blockers and diuretics may reduce the plasma concentration may increase theophyllin simultaneously process.
Oral contraceptive failure may occur simultaneously hryzeofulvin, rifampicin and other antibiotics, especially aminopenitsyliny (such as ampicillin, Amoxilin, pivampicillin) and tetracycline.
There is evidence that the overall effect of vitamin C a major conversion of low high-dose estrogen oral contraceptives oral contraceptives.

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